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Echinacoside (Standard)

CAT: 0804-HY-N0020R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0020R-01Size:5 mg
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Description
Echinacoside (Standard) is the analytical standard of Echinacoside. This product is intended for research and analytical applications. Echinacoside, one of the phenylethanoids isolated from the stems of Cistanche deserticola, effectively inhibits Wnt/β-catenin signaling. Echinacoside elicits neuroprotection by activating Trk receptors and their downstream signal pathways. Antiosteoporotic activity[1][2][3].
CAS Number
82854-37-3
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS) ; Reference Standards; Wnt
Type
Reference Standards
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others; Stem Cell/Wnt
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/echinacoside-standard.html
Smiles
OC1=CC(/C=C/C(O[C@H]2[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](O)[C@H](OCCC4=CC(O)=C(O)C=C4)O[C@@H]2CO[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)=O)=CC=C1O
Molecular Formula
C35H46O20
Molecular Weight
786.73
References & Citations
[1]Zhang D, et al. Echinacoside inhibits amyloid fibrillization of HEWL and protects against Aβ-induced neurotoxicity. Int J Biol Macromol. 2014 Sep 2;72C:243-253.|[2]Zhu M, et al. Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cells from rotenone. J Neurochem. 2013 Feb;124 (4) :571-80.|[3]Li F, et al. Antiosteoporotic activity of echinacoside in ovariectomized rats. Phytomedicine. 2013 Apr 15;20 (6) :549-57.|[4]Li F, et al. Echinacoside promotes bone regeneration by increasing OPG/RANKL ratio in MC3T3-E1 cells. Fitoterapia. 2012 Dec;83 (8) :1443-50.|[5]Li X, et al. Echinacoside ameliorates D-galactosamine plus lipopolysaccharide-induced acute liver injury in mice via inhibition of apoptosis and inflammation. Scand J Gastroenterol. 2014 Aug;49 (8) :993-1000.|[6]Tang C, et al. Echinacoside inhibits breast cancer cells by suppressing the Wnt/β-catenin signaling pathway. Biochem Biophys Res Commun. 2020 Mar 19. pii: S0006-291X (20) 30530-1.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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