Products for Research Use Only
RegisterLogin

Amoxapine

CAT: 0804-HY-B0991-01Size: 250 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0991-01Size:250 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Amoxapine (CL-67772) is a norepinephrine reuptake blocker and a 5-HT2/5-HT3 antagonist. Amoxapine can be used for the research of depression. Amoxapine has antibacterial activity. Amoxapine can enhance the killing effect of macrophages on mycobacterium by inducing autophagy, while protecting the cells from death[1][2][3].
CAS Number
14028-44-5
Product Name Alternative
CL-67772
UNSPSC
12352005
Hazard Statement
H302
Target
Autophagy; Bacterial
Type
Reference compound
Related Pathways
Anti-infection; Autophagy
Applications
Neuroscience-Neuromodulation
Field of Research
Infection; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Amoxapine.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 8.33 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(OC2=CC=CC=C2N=C3N4CCNCC4)C3=C1
Molecular Formula
C17H16ClN3O
Molecular Weight
313.79
Precautions
H302
References & Citations
[1]Wang J, et al. FDA-Approved Amoxapine Effectively Promotes Macrophage Control of Mycobacteria by Inducing Autophagy. Microbiol Spectr. 2022 Oct 26;10 (5) :e0250922.|[2]Delgado C, Manzanares J, Tamargo J, Valenzuela C. Electrophysiological effects of amoxapine in untreated and in amoxapine-pretreated rat atria. Br J Pharmacol. 1986 Feb;87 (2) :317-25.|[3]Maudhuit C, et al. Effects of acute and chronic treatment with amoxapine and cericlamine on the sleep-wakefulness cycle in the rat. Neuropharmacology. 1994 Aug;33 (8) :1017-25.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
B1660-500Amoxapine

Popular Products