RU 58841
CAT:
804-HY-10561-03
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RU 58841
- CAS Number: 154992-24-2
- UNSPSC Description: RU 58841 (PSK-3841) is a specific androgen receptor antagonist or anti-androgen. RU 58841 has a dramatic effect on hair regrowth[1][2][3].
- Target Antigen: Androgen Receptor
- Type: Reference compound
- Related Pathways: Vitamin D Related/Nuclear Receptor
- Field of Research: Endocrinology
- Assay Protocol: https://www.medchemexpress.com/RU-58841.html
- Purity: 99.85
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: FC(F)(C1=C(C=CC(N2C(C(C)(N(C2=O)CCCCO)C)=O)=C1)C#N)F
- Molecular Weight: 369.34
- References & Citations: [1]A controlled study of the effects of RU58841, a non-steroidal antiandrogen, on human hair production by balding scalp grafts maintained on testosterone-conditioned nude mice By De Brouwer, B.; Tetelin, C.; Leroy, T.; Bonfils, A.; Van Neste, D. .From British Journal of Dermatology (1997), 137(5), 699-702.|[2]Münster U, Nakamura C, Haberland A, Jores K, Mehnert W, Rummel S, Schaller M, Korting HC, Zouboulis ChC, Blume-Peytavi U, Sch?fer-Korting M.RU 58841-myristate--prodrug development for topical treatment of acne and androgenetic alopecia.Pharmazie. 2005 Jan;60(1):8-12.|[3]Battmann T, Bonfils A, Branche C, Humbert J, Goubet F, Teutsch G, Philibert D.RU 58841, a new specific topical antiandrogen: a candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism.J Steroid Biochem Mol Biol. 1994 Jan;48(1):55-60.|[4]Pan HJ, et al. Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques. Endocrine. 1998 Aug;9(1):39-43.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Phase 1