Products for Research Use Only
RegisterLogin

Indoline

CAT: 0804-HY-Y0788-01Size: 25 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-Y0788-01Size:25 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Indoline is a derivative of Indole. Indoline can use as the basic structure for CD4 mimetic compounds (CD4mcs), which triggers conformational changes of the HIV-1 envelope glycoprotein (Env) in advance, and causes viral inactivation. Indoline binds to gp120. Indoline CD4mcs can inhibit HIV-1AD8 with an IC50 in the micromolar range[1].
CAS Number
496-15-1
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
HIV
Type
Biochemical Assay Reagents
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/indoline.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : ≥ 200 mg/mL
Smiles
C12=C(NCC2)C=CC=C1
Molecular Formula
C8H9N
Molecular Weight
119.17
Precautions
H302, H315, H319, H335
References & Citations
[1]Fritschi CJ, et al., Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity. Proc Natl Acad Sci U S A. 2023 Mar 28;120 (13) :e2222073120.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

Related Products

CatalogName
HY-D1120Indoine blue
HY-N9130Indicine
HY-A0160Indalpine
HY-N10123-01Indolokine A5
HY-172537Indolimine-214
HY-W001132-01Indole
HY-105529-01Indicine N-oxide
HY-W001132R-01Indole (standard)
HY-W001132S1-01Indole-13C
HY-W001132S3-01Indole-15N

Alternative Products

CatalogName
MBS6042514-01Indoline
I01740-01Indoline 96%
FB1276781- (Bromoacetyl) indoline
452366-01Indoline-2-thione
OR140162- (Hydroxymethyl) indoline
PC103392-016- (Trifluoromethyl) indoline
OR3052584- (Aminomethyl) indoline
GTR19252900-01Indoline-7-carboxaldehyde
OR1057822-01Indoline-5-sulfonamide
PC111713-015- (Trifluoromethoxy) indoline

Popular Products