Octacosane

• Description :

  Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l[1][2][3].

• Product Name Alternative :

  N-Octacosane; NSC 5549

• UNSPSC :

  12352211

• Hazard Statement :

  H304, H411

• Target :

  Bacterial; Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/octacosane.html

• Purity :

  98.0

• Solubility :

  Ethanol : < 1 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CCCCCCCCCCCCCCCCCCCCCCCCCCCC

• Molecular Formula :

  C28H58

• Molecular Weight :

  394.76

• Precautions :

  H304, H411

• References & Citations :

  [1]Carlos R Figueiredo, et al. Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo. Pharmacogn Mag. 2014 Apr;10 (Suppl 2) :S363-76. |[2]S Rajkumar, et al. Mosquitocidal activities of octacosane from Moschosma polystachyum Linn (lamiaceae) . J Ethnopharmacol. 2004 Jan;90 (1) :87-9.|[3]Sameh S M Soliman, et al. Effective targeting of breast cancer cells (MCF7) via novel biogenic synthesis of gold nanoparticles using cancer-derived metabolites. PLoS One. 2020 Oct 6;15 (10) :e0240156.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [630-02-4]