Octacosane

• Description:

  Octacosane is an endogenous metabolite with antibacterial activity. Octacosane shows high cytotoxicity against murine melanoma B16F10-Nex2 cells besides inducing protection against a grafted subcutaneous melanoma. Octacosane has the larvicidal activity against mosquito Culex quinquefasciatus with the LC50 concentration of 7.2 mg/l[1][2][3].

• Product Name Alternative:

  N-Octacosane; NSC 5549

• UNSPSC:

  12352211

• Hazard Statement:

  H304, H411

• Target:

  Bacterial; Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/octacosane.html

• Purity:

  98.0

• Solubility:

  Ethanol : < 1 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  CCCCCCCCCCCCCCCCCCCCCCCCCCCC

• Molecular Formula:

  C28H58

• Molecular Weight:

  394.76

• Precautions:

  H304, H411

• References & Citations:

  [1]Carlos R Figueiredo, et al. Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo. Pharmacogn Mag. 2014 Apr;10 (Suppl 2) :S363-76. |[2]S Rajkumar, et al. Mosquitocidal activities of octacosane from Moschosma polystachyum Linn (lamiaceae) . J Ethnopharmacol. 2004 Jan;90 (1) :87-9.|[3]Sameh S M Soliman, et al. Effective targeting of breast cancer cells (MCF7) via novel biogenic synthesis of gold nanoparticles using cancer-derived metabolites. PLoS One. 2020 Oct 6;15 (10) :e0240156.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [630-02-4]