Products for Research Use Only
RegisterLogin

LY2623091

CAT: 0804-HY-107461Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-107461Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
LY2623091 is a mineralocorticoid receptor antagonist for the treatment of refractory hypertension. LY2623091 exhibits CYP3A4-dependent clearance and synergistic effects with CYP3A4 inhibitors[1][2].
CAS Number
1162264-07-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ly2623091.html
Smiles
FC1=CC=C(C(OCC2=CC=CC=C/32)=C1)C3=C\C4=CC=C(N([C@H](C)CN5CCOCC5)C(NC(N)=O)=N6)C6=C4
Molecular Formula
C30H30FN5O3
Molecular Weight
527.59
Precautions
P261-P280-P302+P352
References & Citations
[1]Dickinson G L, et al. Physiologically based pharmacokinetic modeling to understand the observed drug–drug interaction of LY2623091 with CYP3A inhibitors itraconazole and diltiazem[J]. International journal of Pharmacokinetics, 2017, 2 (4) : 233-245.|[2]Kocienski P. Synthesis of LY2623091[J]. Synfacts, 2017, 13 (05) : 0451.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Related Products

CatalogName
HY-103357ALY262691

Alternative Products

CatalogName
T88208-01LY2623091

Popular Products