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(S) -Terazosin

CAT: 0804-HY-B0371D-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0371D-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) -Terazosin is an active S-enantiomer of Terazosin. (S) -Terazosin is a potent and high-affinity α-adrenoceptor antagonist with Ki values of 3.91 nM, 0.79 nM and 1.16 nM for α1a, α1b and α1d-adrenoceptor, respectively. (S) -Terazosin also has high-affinity for α2a, α2B and α2c-adrenoceptor with Ki values of 729 nM, 3.5 nM and 46.4 nM, respectively[1].
CAS Number
109351-33-9
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/s-terazosin.html
Purity
99.71
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(N1CCN(C2=NC(N)=C3C=C(OC)C(OC)=CC3=N2)CC1)[C@H]4OCCC4
Molecular Formula
C19H25N5O4
Molecular Weight
387.43
Precautions
H315, H319, H320
References & Citations
[1]Hancock AA, et al. Actions of terazosin and its enantiomers at subtypes of alpha 1- and alpha 2-adrenoceptors in vitro. J Recept Signal Transduct Res. 1995 Sep-Dec;15 (7-8) :863-85.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
α adrenergic receptor

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