Dehydro Nifedipine-13C,d3

Dehydro Nifedipine-13C,d3

• CAS Number: 325484-33-1
• UNSPSC Description: Dehydro Nifedipine-13C,d3 is a deuterated labeled Dehydro Nifedipine[1]. Dehydro nifedipine (BAY-b 4759) is a metabolite of Nifedipine (HY-B0284). Nifedipine (BAY-a-1040) is a potent calcium channel blocker and an agent of choice for cardiac insufficiencies[2].
• Target Antigen: Drug Metabolite; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Smiles: O=C(C([13C]([2H])([2H])[2H])=CN1[C@@H](C2)O[C@@H]([C@H]2N=[N+]=[N-])CO)NC1=O
• Molecular Weight: 271.25
• References & Citations: [1]Dipanjan Goswami, et al. Method Development Challenges and Regulatory Expectation in Nifedipine. International Journal of Pharmacokinetics, Volume 2, 2017 - Issue 1.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported