Phospho-RPS6 (S240 + S244) Recombinant Rabbit Monoclonal Antibody [PS00-65]

Phospho-RPS6 (S240 + S244) Recombinant Rabbit Monoclonal Antibody [PS00-65]

• Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
• Product Name Alternative: 40S ribosomal protein S6 antibody Air8 antibody NP33 antibody Phosphoprotein NP33 antibody Pp30 antibody Ribosomal protein S6 antibody RP S6 antibody rps6 antibody RS6 antibody RS6_HUMAN antibody S6 antibody S6 Ribosomal Protein antibody
• Abbreviation: RPS6
• CAS Number: 9000-83-3
• Swiss Prot: P62753 Human, P62754 Mouse, P62755 Rat
• Cellular Locus: Cytosol, Endoplasmic reticulum, Nucleus.
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide within Human RPS6 aa 200 to the C-terminus (phospho S240 + S244).
• Isotype: IgG
• Clone: PS00-65
• Conjugation: Non-conjugated
• Type: Recombinant Rabbit monoclonal Antibody
• Applications: WB, IHC-P, IF-Cell
• Positive Control: A431 cell lysates, human colon carcinoma tissue, human pancreas tissue, mouse hippocampus tissue, mouse brain tissue, SK-Br-3.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000 ;IHC-P: 1:5,000-10,000 ;IF-Cell: 1:50
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 29 kDa.
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes