Products for Research Use Only
RegisterLogin

4-Hydroxyatomoxetine

CAT: 0804-HY-133116-01Size: 500 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-133116-01Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
4-Hydroxyatomoxetine is an active metabolite of Atomoxetine. 4-Hydroxyatomoxetine is metabolized by the enzyme cytochrome P450 2D6 (CYP2D6) . Atomoxetine hydrochloride is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5 nM, 77 nM and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively) [1][2].
CAS Number
435293-66-6
UNSPSC
12352005
Hazard Statement
H302-H319-H361
Target
Adrenergic Receptor; Drug Metabolite
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/4-hydroxyatomoxetine.html
Purity
97.04
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C(O[C@@H](C2=CC=CC=C2)CCNC)C(C)=C1
Molecular Formula
C17H21NO2
Molecular Weight
271.36
Precautions
P264-P270-P280-P305+P351+P338-P330-P405-P501
References & Citations
[1]JT Brown, Single Dose Pharmacokinetics of Atomoxetine in Children.|[2]Bymaster FP, Katner JS, Nelson DL et al. Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder. Neuropsychopharmacology. 2002 Nov;27 (5) :699-711.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W099255-01Ethyl 4,4,4,4',4',4'-hexafluoro-DL-valinate
HY-W7200064,4'-Diapo-ω, ω-carotene-4,4'-dial
HY-77910-014- (4-Bromophenyl) -4-hydroxypiperidine
HY-W0142264,4'-Dihydroxybenzophenone
HY-N90384',4''-Dihydroxyanigorootin
HY-W011927-014,4'-Sulfonyldiphenol
HY-W2697474,4'-Dimethoxyoctafluorobiphenyl
HY-W0119184,4'-Dichlorobenzophenone
HY-136064-014,4'-Dimethoxychalcone
HY-103610-014,4'-Dimethoxybenzil

Alternative Products

CatalogName
T10145-014-Hydroxyatomoxetine
MBS57659304-Hydroxyatomoxetine D3
CS-O-50271N-Desmethyl-4-hydroxyatomoxetine-O-glucuronide
PC52154,4,4,4',4',4'-Hexafluorovaline hydrochloride
PC64124,4,4-Trifluorobutyl 4,4,4-trifluorobutanoate
OR1011273-014,4',4'',4'''-Methanetetrayltetrabenzaldehyde
OR1011238-014,4,4,4-Silanetetrayltetrabenzaldehyde
OR1011275-014,4',4'',4'''-Methanetetrayltetraphenol
PC4810-014,4,4,4',4',4'-Hexafluoro-DL-valine
PC450233-014,4,4,4',4',4'-Hexafluorovaline, ethyl ester

Popular Products