13(S)-HPODE

• UNSPSC Description:

  13(S)-HPODE is a linoleic acid metabolite found in several plants and mammals.

• Target Antigen:

  EGFR; Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  JAK/STAT Signaling;Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/13_S_-HPODE.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(O)=O

• Molecular Weight:

  312.44

• References & Citations:

  [1]Gardner HW, et al. Soybean lipoxygenase-1 enzymically forms both (9S)- and (13S)-hydroperoxides from linoleic acid by a pH-dependent mechanism. Biochim Biophys Acta. 1989 Feb 20;1001(3):274-81.|[2]Reinaud O, et al. Oxidative metabolism of linoleic acid by human leukocytes. Biochem Biophys Res Commun. 1989 Jun 15;161(2):883-91.|[3]Glasgow WC, et al. The linoleic acid metabolite, (13S)-hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenotypes. J Biol Chem. 1997 Aug 1;272(31):19269-76.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  33964-75-9