13 (S) -HPODE

• Description :

  13 (S) -HPODE is a linoleic acid metabolite found in several plants and mammals.

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  EGFR; Endogenous Metabolite

• Type :

  Natural Products

• Related Pathways :

  JAK/STAT Signaling; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/13_S_-HPODE.html

• Concentration :

  320.06 μM * 500 μL in Ethanol

• Purity :

  95.0

• Solubility :

  10 mM in DMSO

• Smiles :

  CCCCC[C@H](OO)/C=C/C=C\CCCCCCCC(O)=O

• Molecular Formula :

  C18H32O4

• Molecular Weight :

  312.44

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Gardner HW, et al. Soybean lipoxygenase-1 enzymically forms both (9S) - and (13S) -hydroperoxides from linoleic acid by a pH-dependent mechanism. Biochim Biophys Acta. 1989 Feb 20;1001 (3) :274-81.|[2]Reinaud O, et al. Oxidative metabolism of linoleic acid by human leukocytes. Biochem Biophys Res Commun. 1989 Jun 15;161 (2) :883-91.|[3]Glasgow WC, et al. The linoleic acid metabolite, (13S) -hydroperoxyoctadecadienoic acid, augments the epidermal growth factor receptor signaling pathway by attenuation of receptor dephosphorylation. Differential response in Syrian hamster embryo tumor suppressor phenotypes. J Biol Chem. 1997 Aug 1;272 (31) :19269-76.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Solution, -20°C, 2 years

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [33964-75-9]