Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE

• CAS Number: 1638970-46-3
• UNSPSC Description: Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A)[1].
• Target Antigen: Drug-Linker Conjugates for ADC
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mc-alanyl-alanyl-asparagine-pab-mmae.html
• Solubility: DMSO : 180 mg/mL (ultrasonic)
• Smiles: C[C@@H](C(N[C@H](C)[C@H](C1=CC=CC=C1)O)=O)[C@H]([C@@](CCC2)([H])N2C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CC(N)=O)NC([C@H](C)NC([C@H](C)NC(CCCCCN(C4=O)C(C=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O)OC
• Molecular Weight: 1316.58
• References & Citations: [1]Liu Chen, et al. Tumor microenvironment specific activated micromolecular targeted conjugate and application thereof. CN104147612A.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported