Products for Research Use Only

Maplirpacept

CAT: 0804-HY-P990707-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P990707-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Maplirpacept (TTI-622; PF-07901801) is a fusion protein consisting of the CD47-binding domain of human SIRPα linked to the Fc region of human IgG4. Maplirpacept enhances phagocytosis by blocking CD47[1][2].
CAS Number
2631667-06-4
Product Name Alternative
TTI-622; PF-07901801
UNSPSC
12352203
Target
CD47
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/maplirpacept.html
Purity
97.73
References & Citations
[1]Maplirpacept|[2]Daron G. Street, et al. A phase I/II study of maplirpacept in combination with pegylated liposomal doxorubicin (PLD) in patients with platinum-resistant ovarian cancer (OC) : Phase 1 results.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2