CIF1

CIF1 Catalog number: MDP0850 CAS Number: 95991-05-2 Sequence: Asp-Tyr(SO3H)-Gly-Asn-Asn-Ser-Hyp-Ser-Hyp-Arg-Leu-Glu-Arg-Pro-Pro-Phe-Lys-Leu-Ile-Pro-Asn Amount: 100 ug Molecular Weight: 2523.6 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: -20 °C WARNING: For in vitro Research Use Only. NOT for use on humans or animals. Grade: Biotechnology grade. All products are highly pure. References: 1: Zhou Q, An T, Pham KTM, Hu H, Li Z. The CIF1 protein is a master orchestrator of trypanosome cytokinesis that recruits several cytokinesis regulators to the cytokinesis initiation site J Biol Chem. 2018 Oct 19;293(42):16177-16192. 2: Hu H, Majneri P, Li D, Kurasawa Y, An T, Dong G, Li Z. Functional analyses of the CIF1-CIF2 complex in trypanosomes identify the structural motifs required for cytokinesis J Cell Sci. 2017 Dec 15;130(24):4108-4119. 3: Kurasawa Y, Hu H, Zhou Q, Li Z. The trypanosome-specific protein CIF3 cooperates with the CIF1 protein to promote cytokinesis in Trypanosoma brucei J Biol Chem. 2018 Jun 29;293(26):10275-10286. 4: Kurasawa Y, Lee KJ, Hu H, Pham KTM, Li Z. Polo-like kinase and Aurora B kinase phosphorylate and cooperate with the CIF1-CIF2 complex to promote cytokinesis initiation in Trypanosoma brucei Open Biol. 2022 Oct;12(10):220197. 5: Hazell BW, Nevalainen H, Attfield PV. Evidence that the Saccharomyces cerevisiae CIF1 (GGS1/TPS1) gene modulates heat shock response positively FEBS Lett. 1995 Dec 27;377(3):457-60. 6: Hazell BW, Kletsas S, Nevalainen H, Attfield PV. Involvement of CIF1 (GGS1/TPS1) in osmotic stress response in Saccharomyces cerevisiae FEBS Lett. 1997 Sep 8;414(2):353-8. 7: González MI, Stucka R, Blázquez MA, Feldmann H, Gancedo C. Molecular cloning of CIF1, a yeast gene necessary for growth on glucose Yeast. 1992 Mar;8(3):183-92. 8: Hu H, An T, Kurasawa Y, Zhou Q, Li Z. The trypanosome-specific proteins FPRC and CIF4 regulate cytokinesis initiation by recruiting CIF1 to the cytokinesis initiation site J Biol Chem. 2019 Nov 8;294(45):16672-16683. 9: Zhou Q, Hu H, Li Z. An EF-hand-containing Protein in Trypanosoma brucei Regulates Cytokinesis Initiation by Maintaining the Stability of the Cytokinesis Initiation Factor CIF1 J Biol Chem. 2016 Jul 8;291(28):14395-409. 10: Blázquez MA, Gancedo C. Identification of extragenic suppressors of the cif1 mutation in Saccharomyces cerevisiae Curr Genet. 1994 Feb;25(2):89-94.
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Catalog Number: MDP0850 (100 ug)

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