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Topiramate

CAT: 0026-B3280-50Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0026-B3280-50Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Topiramate is a potent antiepileptic drug with a broad spectrum of activity. Topiramate acts as an antagonist of GluK1 kainate receptors (IC50 = 0.46 μM); also acts as a positive allosteric modulator of GABAA receptor-mediated currents, inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels. Also inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2 μM at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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