Koaburaside

CAT: 0804-HY-N3421Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N3421Size:1 Each
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Description
Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC50 of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase[1].
CAS Number
[41653-73-0]
UNSPSC
12352005
Target
Influenza Virus; Interleukin Related; TNF Receptor
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/koaburaside.html
Solubility
10 mM in DMSO
Smiles
COC1=C(O)C(OC)=CC(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)=C1
Molecular Formula
C14H20O9
Molecular Weight
332.30
References & Citations
[1]He Y, et al. Phenolic compounds from Eurycorymbus cavaleriei. J Asian Nat Prod Res. 2011 Jun;13 (6) :575-80.|[2]Subedi L, et al. Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro. Phytomedicine. 2016 Jul 15;23 (8) :872-81.|[3]Choi HG, et al. Phenolic glycosides from Lindera obtusiloba and their anti-allergic inflammatory activities. Nat Prod Commun. 2013 Feb;8 (2) :181-2.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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