Koaburaside

• Description :

  Koaburaside is a cytoprotective and anti-inflammatory natural compound. Koaburaside shows antioxidant activity with an IC50 of 9.0 μM for DPPH-free radical scavenging assay. Koaburaside inhibits histamine release and expressions of IL-6 and TNF-α in human mast cells. Koaburaside also effectively inhibits influenza A neuraminidase[1].

• UNSPSC :

  12352005

• Target :

  Influenza Virus; Interleukin Related; TNF Receptor

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Apoptosis; Immunology/Inflammation

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/koaburaside.html

• Solubility :

  10 mM in DMSO

• Smiles :

  COC1=C(O)C(OC)=CC(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)=C1

• Molecular Formula :

  C14H20O9

• Molecular Weight :

  332.30

• References & Citations :

  [1]He Y, et al. Phenolic compounds from Eurycorymbus cavaleriei. J Asian Nat Prod Res. 2011 Jun;13 (6) :575-80.|[2]Subedi L, et al. Anti-neuroinflammatory and neuroprotective effects of the Lindera neesiana fruit in vitro. Phytomedicine. 2016 Jul 15;23 (8) :872-81.|[3]Choi HG, et al. Phenolic glycosides from Lindera obtusiloba and their anti-allergic inflammatory activities. Nat Prod Commun. 2013 Feb;8 (2) :181-2.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [41653-73-0]