Bursin

• Description:

  Bursin is a peptide that can be isolated from the bursa of Fabricius of chicken. Bursin induces the phenotypic differentiation of mammalian and avian B precursor cells. Bursin also increases cyclic guanosine monophosphate in cells of the human B-cell line Daudi, its derivatives are able to protect against infection by amplifying the immune response induced by H9N2[1].

• UNSPSC:

  12352209

• Target:

  Influenza Virus

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bursin.html

• Purity:

  99.35

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(CNC([C@@H](NC([C@@H](N)CCCCN)=O)CC1=CNC=N1)=O)N

• Molecular Formula:

  C14H25N7O3

• Molecular Weight:

  339.39

• References & Citations:

  [1]Audhya T, et al. Tripeptide structure of bursin, a selective B-cell-differentiating hormone of the bursa of fabricius. Science. 1986 Feb 28;231 (4741) :997-9.|[2]Wang C, et al. Bursin-like peptide (BLP) enhances H9N2 influenza vaccine induced humoral and cell mediated immune responses. Cell Immunol. 2014 Nov-Dec;292 (1-2) :57-64.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  60267-34-7