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Thiazolyl Blue

CAT: 0804-HY-15924-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15924-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis[1].
CAS Number
298-93-1
Product Name Alternative
MTT; Thiazolyl Blue Tetrazolium (bromide) ; Methylthiazolyldiphenyl-tetrazolium (bromide)
UNSPSC
12171500
Hazard Statement
H315, H319, H335, H341
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/MTT.html
Purity
99.84
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 0.88 mg/mL (ultrasonic; warming)
Smiles
CC1=C(C)N=C(N2N=C(C3=CC=CC=C3)N=[N+]2C4=CC=CC=C4)S1.[Br-]
Molecular Formula
C18H16BrN5S
Molecular Weight
414.32
Precautions
H315, H319, H335, H341
References & Citations
[1]Berridge MV, et al. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev. 2005;11:127-52.|[2]Berridge MV, et al. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev. 2005;11:127-52.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported