Bergenin

• Description:

  Bergenin is a cytoprotective and antioxidative polyphenol found in many medicinal plants. Bergenin has a wide spectrum activities such as hepatoprotective, antiinflammatory, immunomodulatory, antitumor, antiviral, and antifungal properties[1][2].

• Product Name Alternative:

  Cuscutin

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H335

• Target:

  Apoptosis; Autophagy; Bacterial; Fungal; NF-κB; Virus Protease

• Type:

  Natural Products

• Related Pathways:

  Anti-infection; Apoptosis; Autophagy; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/Bergenin.html

• Purity:

  99.34

• Solubility:

  DMSO : 103.3 mg/mL (ultrasonic; warming)

• Smiles:

  OC1=C(OC)C(O)=C([C@@]2([H])[C@@](OC3=O)([H])[C@@H](O)[C@H](O)[C@@H](CO)O2)C3=C1

• Molecular Formula:

  C14H16O9

• Molecular Weight:

  328.27

• Precautions:

  H315, H319, H335

• References & Citations:

  [1]Shi X, et al. Anticancer activity of bergenin against cervical cancer cells involves apoptosis, cell cycle arrest, inhibition of cell migration and the STAT3 signalling pathway. Exp Ther Med. 2019 May;17 (5) :3525-3529.|[2]Yun J, et al. Bergenin decreases the morphine-induced physical dependence via antioxidative activity in mice. Arch Pharm Res. 2015 Jun;38 (6) :1248-54.|[3]de Oliveira CM, et al. Antinociceptive properties of bergenin. J Nat Prod. 2011 Oct 28;74 (10) :2062-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  Launched

• CAS Number:

  [477-90-7]