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NU074381b

CAT: 0804-HY-168529-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-168529-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NU074381b (compound 5b) is a potent S100A4 inhibitor. NU074381b inhibits S100A4-NMII complex formation with an IC50 value of 0.48 µM. NU074381b inhibits cell proliferation and migration[1].
UNSPSC
12352211
Target
Myosin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nu074381b.html
Purity
98.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1C[C@@H](CN1C(CCl)=O)C2=CC=CC=C2)NC3CCCC4=C3C=CC=C4
Molecular Formula
C23H25ClN2O2
Molecular Weight
396.91
References & Citations
[1]Giroud C, et al. Covalent Inhibitors of S100A4 Block the Formation of a Pro-Metastasis Non-Muscle Myosin 2A Complex. J Med Chem. 2024 Oct 19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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