Ligustrazine

CAT: 0804-HY-N0264-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0264-01Size:50 mg
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Description
Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong) [1], is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats[2][3].
CAS Number
[1124-11-4]
Product Name Alternative
Chuanxiongzine; Tetramethylpyrazine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Tetramethylpyrazine.html
Purity
99.99
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1=C(C)N=C(C)C(C)=N1
Molecular Formula
C8H12N2
Molecular Weight
136.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhao Y, et al. Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii) : Current Status and Perspective. Oxid Med Cell Longev. 2016;2016:2124638.|[2]Wu W, et al. Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway. Behav Brain Res. 2013 Sep 15;253:212-6.|[3]Kao TK, et al. Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. Exp Neurol. 2013 Sep;247:188-201.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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