Phosphoramidon

• Description :

  Phosphoramidon Catalog number: MDP0444 CAS Number: 3106-85-2 Sequence: N-(α-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan disodium salt dihydrate Amount: 5 mg Molecular Weight: 541.2 g/mol Supplied as: Powder Applications: molecular tool for various biochemical applications Storage: -20 °C WARNING: For in vitro Research Use Only. NOT for use on humans or animals. Grade: Biotechnology grade. All products are highly pure. References: 1: Goblirsch BR, Arachea BT, Councell DJ, Wiener MC. Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24 Acta Crystallogr D Struct Biol. 2018 Aug 1;74(Pt 8):739-747. 2: Bhavsar TM, Cerreta JM, Liu M, Reznik SE, Cantor JO. Phosphoramidon, an endothelin-converting enzyme inhibitor, attenuates lipopolysaccharide-induced acute lung injury Exp Lung Res. 2008 Mar;34(3):141-54. 3: Wu-Wong JR, Chiou WJ, Opgenorth TJ. Phosphoramidon modulates the number of endothelin receptors in cultured Swiss 3T3 fibroblasts Mol Pharmacol. 1993 Aug;44(2):422-9. 4: Labiuk SL, Sygusch J, Grochulski P. Structures of soluble rabbit neprilysin complexed with phosphoramidon or thiorphan Acta Crystallogr F Struct Biol Commun. 2019 Jun 1;75(Pt 6):405-411. 5: Jelicks LA, Chandra M, Shtutin V, Petkova SB, Tang B, Christ GJ, Factor SM, Wittner M, Huang H, Douglas SA, Weiss LM, Orleans-Juste PD, Shirani J, Tanowitz HB. Phosphoramidon treatment improves the consequences of chagasic heart disease in mice Clin Sci (Lond). 2002 Aug;103 Suppl 48:267S-271S. 6: dos Santos MH, da Costa AF, Ferreira BJ, Souza SL, da Silva Lannes P, Santos GS, Mattos-Guaraldi AL, Nagao PE. A phosphoramidon-sensitive metalloprotease induces apoptosis of human endothelial cells by Group B Streptococcus Antonie Van Leeuwenhoek. 2013 Dec;104(6):1125-33. 7: Isaka D, Emoto N, Raharjo SB, Yokoyama M, Matsuo M. The effects of phosphoramidon on the expression of human endothelin-converting enzyme-1 (ECE-1) isoforms J Cardiovasc Pharmacol. 2003 Jul;42(1):136-41. 8: Hanson LR, Hafez D, Svitak AL, Burns RB, Li X, Frey WH 2nd, Marr RA. Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice J Mol Neurosci. 2011 Mar;43(3):424-7. 9: Matsumaru K, Kashimura H, Hassan M, Nakahara A, Goto K, Fukutomi H, Muto H, Tanaka N. Phosphoramidon, an inhibitor of endothelin-converting enzyme, prevents indomethacin-induced gastric mucosal damage in rats Life Sci. 1998;62(7):PL79-84. 10: Fujita K, Matsumura Y, Kita S, Hisaki K, Takaoka M, Morimoto S. Phosphoramidon-sensitive conversion of big endothelin-1 and degradation of endothelin-1 in rat kidney Hypertension. 1994 Aug;24(2):227-33.
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• Short Description :

  Catalog Number: MDP0444 (5 mg)

• Weight :

  0.15

• Length :

  2

• Width :

  0.5

• Height :

  0.5