JAK2 JH2 Tracer

JAK2 JH2 Tracer

• CAS Number: 2101955-00-2
• UNSPSC Description: JAK2 JH2 Tracer (Tracer 5) is a fluorescent probe for JAK2 JH2 domain, with a Kd of value 0.2 μM[1][2].
• Target Antigen: JAK
• Type: Dye Reagents
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/JAK2_JH2_Tracer.html
• Purity: 98.03
• Solubility: DMSO : ≥ 83.3 mg/mL
• Smiles: S=C(NC1=CC2=C(C3(C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)OC2=O)C=C1)N(CC6=CC=C(NC7=NN(C(C8=C(F)C=CC=C8F)=O)C(N)=N7)C=C6)C
• Molecular Weight: 747.73
• References & Citations: [1]Newton AS, et al. JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules. ACS Med Chem Lett. 2017 May 17;8(6):614-617.|[2]Ihle JN, Gilliland DG. Jak2: normal function and role in hematopoietic disorders. Curr Opin Genet Dev. 2007 Feb;17(1):8-14.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported