PGAM1-IN-2

• Description:

  PGAM1-IN-2 is a phosphoglycerate mutase 1 (PGAM1) inhibitor with an IC50 of 2.1 μM[1].

• UNSPSC:

  12352005

• Target:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pgam1-in-2.html

• Purity:

  98.02

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles:

  O=C1C2=C(O)C=C(NS(C3=CC=C(C4=CC=CC=C4)C=C3)(=O)=O)C=C2OC5=C1C=C([N+]([O-])=O)C=C5

• Molecular Formula:

  C25H16N2O7S

• Molecular Weight:

  488.47

• References & Citations:

  [1]Wang P, et al. The Design and Synthesis of N-Xanthone Benzenesulfonamides as Novel Phosphoglycerate Mutase 1 (PGAM1) Inhibitors. Molecules. 2018 Jun 8;23 (6) . pii: E1396.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2438637-66-0]