Casein kinase 1δ-IN-6

Casein kinase 1δ-IN-6

• CAS Number: 1579991-01-7
• UNSPSC Description: Casein kinase 1δ-IN-6 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 23 nM. Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory properties both in vitro and in vivo. Casein kinase 1δ-IN-6 is a promising drug candidate and can be used for neurodegenerative diseases research.
• Target Antigen: Casein Kinase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Stem Cell/Wnt
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/casein-kinase-1δ-in-6.html
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O=C(CC1=CC(Cl)=CC=C1)NC2=NC3=C(S2)C=C(C(F)(F)F)C=C3
• Molecular Weight: 370.78
• References & Citations: [1]José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease. ACS Omega. 2017 Aug 31;2(8):5215-5220.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported