15 (R) -PTA2

CAT: 0804-HY-137227-01Size: 500 µgDry Ice: NoHazardous: No
CAT#:0804-HY-137227-01Size:500 µg
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Description
15 (R) -PTA2 (15 (R) -Pinanethromboxane A2) is an antithrombotic agent that inhibits platelet aggregation. 15 (R) -PTA2 inhibits stable prostaglandin endoperoxide analog-induced constriction of feline coronary arteries and stabilizes hepatic lysosomes. 15 (R) -PTA2 also inhibits thromboxane synthase but has no effect on prostacyclin synthase[1].
CAS Number
[71154-83-1]
Product Name Alternative
15 (R) -Pinanethromboxane A2
UNSPSC
12352211
Hazard Statement
H225-H319
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/15-r-pta2.html
Solubility
10 mM in DMSO
Smiles
OC(CCC/C=C\C[C@H]1[C@@]2([H])C(C)([C@](C[C@@H]1/C=C/[C@H](O)CCCCC)([H])C2)C)=O
Molecular Formula
C24H40O3
Molecular Weight
376.57
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]Nicolaou KC, et al. Synthesis and biological properties of pinane-thromboxane A2, a selective inhibitor of coronary artery constriction, platelet aggregation, and thromboxane formation. Proc Natl Acad Sci U S A. 1979 Jun;76 (6) :2566-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
TSW-00099PTA2
sc-201177PTA2 (Pinane thromboxane A2)

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