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Arbutamine

CAT: 0804-HY-16056-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-16056-01Size:500 µg
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Description
Arbutamine is a short-acting, potent and nonselective β-adrenoceptor agonist. Arbutamine stimulates cardiac β1-, tracheal β2-, and adiopocyte β3- adrenergic receptors. Arbutamine provides cardiac stress increases heart rate, cardiac contractility, and systolic blood pressure. Arbutamine can be used for cardiac stress agent [1][2][3].
CAS Number
128470-16-6
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/arbutamine.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
OC1=CC=C([C@@H](O)CNCCCCC2=CC=C(O)C=C2)C=C1O
Molecular Formula
C18H23NO4
Molecular Weight
317.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Ruiz M, et al. Arbutamine stress perfusion imaging in dogs with critical coronary artery stenoses: (99m) Tc-sestamibi versus (201) Tl. J Nucl Med. 2002 May;43 (5) :664-70.|[2]Nagarajan R, et al. A novel catecholamine, arbutamine, for a pharmacological cardiac stress agent. Cardiovasc Drugs Ther. 1996 Mar;10 (1) :31-8.|[3]Abou-Mohamed G, et, al. Characterization of the adrenergic activity of arbutamine, a novel agent for pharmacological stress testing. Cardiovasc Drugs Ther. 1996 Mar;10 (1) :39-47.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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