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Recombinant Human SMAD4

CAT: 0710-P1445-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0710-P1445-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
DPC4, hSMAD4, JIP, MAD homolog 4, MADH4, Mothers against DPP homolog 4, SMAD 4, SMAD family member 4, SMAD4
UniProt
Q13485
Expression Region
13-227
Host
E.Coli
Tag
N-terminal His Tag
Applications
Western Blot, ELISA
Field of Research
Epigenetics, Signal Transduction, Metabolism, Cardiovascular, Immunology, Cancer, Developmental biology
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Lyophilized powder
Reconstitution
Centrifuge the vial before opening, reconstitute in sterile distilled water to a concentration of 0.1-1 mg/ml by gently pipetting 2-3 times, don't vortex.
Molecular Weight
25.6 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
The lyophilized protein is stable at -20 °C for up to 1 year. For extended storage, it is recommended to further dilute in working aliquots after reconstitution. The protein solution is stable at ≤ -20 °C for 3 months, or 2-7 days at 2-8 °C under sterile conditions.Avoid repeated freeze/thaw cycle.
Formulation
Lyophilized from a 0.2 μm filtered solution of 10 mM Hepes, 150 mM NaCl with 5% trehalose, pH 7.4.
Organism Species
Human

UniProtKB · Q13485

SMAD family member 4

SMAD4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13485
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SMAD4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SMAD 4, hSMAD4
EC number
—
Processing
—
Secondary accessions
A8K405
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Cellular component

CytoplasmNucleus

Disease

Disease variant

Molecular function

DNA-binding

Ligand

Metal-bindingZinc

Biological process

TranscriptionTranscription regulation