ELOVL6-IN-4

ELOVL6-IN-4

• CAS Number: 1170321-92-2
• UNSPSC Description: ELOVL6-IN-4 is a potent, selective, and orally active long chain fatty acid elongase 6 (ELOVL6) inhibitor with IC50s of 79 nM and 94 nM for human and mouse ELOVL6, respectively. ELOVL6-IN-4 shows excellent selectivity over the other human ELOVL subtypes (ELOVL1, -2, -3, and -5) and mouse ELOVL3[1].
• Target Antigen: ELOVL
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/elovl6-in-4.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: FC(F)(F)C(C=C1)=CC=C1NC(N2[C@@]3([H])C[C@@H](C[C@]2([H])CC3)S(=O)(C4=CC=CC=N4)=O)=O
• Molecular Weight: 439.45
• References & Citations: [1]Tsuyoshi Nagase, et al. Synthesis and biological evaluation of a novel 3-sulfonyl-8-azabicyclo[3.2.1]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors. J Med Chem. 2009 Jul 23;52(14):4111-4.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported