GLP-1R agonist 22

• UNSPSC Description:

  GLP-1R agonist 22 (Compound I-135) is an agonist for glucagon-like peptide-1 receptor (GLP-1 receptor), with EC50 of 0.0165 nM[1].

• Target Antigen:

  GLP Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/glp-1r-agonist-22.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC(F)=C(COC2=C(C#N)C=C(CCN(CC3=NC4=CC=C(C(O)=O)C=C4N3C[C@@H]5CCO5)[C@H]6C)C6=N2)C=C1

• Molecular Weight:

  576.02

• References & Citations:

  [1]Kitamura FY, et al., Fused ring compound having glp-1 receptor agonist effect. WO2024063143A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported