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HS38

CAT: 0804-HY-15847-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-15847-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HS38 is a potent, selective, and ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) and zipper-interacting protein kinase (ZIPK, also called DAPK3), with Kds of 300 nM and 280 nM, respectively. HS38 is also a PIM3 inhibitor with an IC50 of 200 nM. HS38 can be used for the research of smooth muscle related disorders[1].
CAS Number
1030203-81-6
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
DAPK
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hs38.html
Concentration
10mM
Purity
99.91
Solubility
DMSO : 7.14 mg/mL (ultrasonic)
Smiles
CC(SC1=NC(N(C2=CC=CC(Cl)=C2)N=C3)=C3C(N1)=O)C(N)=O
Molecular Formula
C14H12ClN5O2S
Molecular Weight
349.80
Precautions
H315, H319, H335
References & Citations
[1]David A Carlson, et al. Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor. ACS Chem Biol. 2013 Dec 20; 8 (12) : 2715–2723.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
BA3396-10HS38

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