Mouse IL-21 Recombinant Rabbit Monoclonal Antibody [PSH04-74] - BSA and Azide free (Capture)

• Description:

  Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene. Interleukin-21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. This cytokine induces cell division/proliferation in its target cells. The IL-21 receptor (IL-21R) is expressed on the surface of T, B and NK cells. IL-21r is similar in structure to the receptors for other type I cytokines like IL-2R or IL-15 and requires dimerization with the common gamma chain (γc) in order to bind IL-21. When bound to IL-21, the IL-21 receptor acts through the Jak/STAT pathway, utilizing Jak1 and Jak3 and a STAT3 homodimer to activate its target genes.

• Product Name Alternative:

  CVID11 antibody IL 21 antibody IL-21 antibody Il21 antibody IL21_HUMAN antibody Interleukin 21 antibody Interleukin-21 antibody interleukin-21 isoform antibody Interleukin21 antibody OTTHUMP00000164088 antibody Za11 antibody

• Abbreviation:

  Interleukin-21 IL-21 Il21

• Swiss Prot:

  Q9ES17 Mouse

• Cellular Locus:

  Secreted.

• Host:

  Rabbit

• Species Reactivity:

  Mouse

• Immunogen:

  Recombinant protein within Mouse IL-21 aa 18-146 (Q9ES17).

• Isotype:

  IgG

• Clone:

  PSH04-74

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  ELISA (Cap)

• Positive Control:

  Recombinant Mouse IL-21 protein (HA210801).

• Concentration:

  1 mg/mL

• Dilution:

  ELISA (Cap): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH04-75] to Mouse IL-21 antibody (Detector) (HA722175) and recombinant Mouse IL-21 protein as the standard (HA210801). The reference range value is 20.6-2,000 pg/ml.

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4).

• Molecular Weight:

  Predicted band size: 17 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3