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Raspberry ketone glucoside

CAT: 0804-HY-N6069-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N6069-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Raspberry ketone glucoside is a melanogenesis inhibitor. Raspberry ketone glucoside inhibits melanogenesis by activating the IL6/JAK1/STAT3 pathway, inhibiting the transcriptional activity of MITFa, and its downstream expression levels of the TYR and TYRP1a genes. Raspberry ketone glucoside shows remarkable whitening activity on both B16F10 cells in vitro and zebrafish model in vivo[1].
CAS Number
38963-94-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related; JAK; STAT
Type
Natural Products
Related Pathways
Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/raspberry-ketone-glucoside.html
Concentration
10mM
Purity
99.52
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(CCC(C=C1)=CC=C1O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)=O
Molecular Formula
C16H22O7
Molecular Weight
326.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Guo QQ, et al. Raspberry ketone glucoside suppresses melanin synthesis through IL6/JAK1/STAT3 signal pathway. Eur Rev Med Pharmacol Sci. 2023 May;27 (9) :4254-4268.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported