ICAM-1-IN-1
CAT:
804-HY-U00003-01
Size:
25 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ICAM-1-IN-1
- CAS Number: 251994-14-6
- UNSPSC Description: ICAM-1-IN-1 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC50 values of 7 and 5 nM, respectively.
- Target Antigen: Integrin
- Type: Reference compound
- Related Pathways: Cytoskeleton
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/Thieno[2,3-c]pyridine-2-carboxamide,_4-_4-bromophenoxy_-N-methyl-.html
- Purity: 99.93
- Solubility: DMSO : ≥ 135 mg/mL
- Smiles: O=C(C(S1)=CC2=C1C=NC=C2OC3=CC=C(Br)C=C3)NC
- Molecular Weight: 363.23
- References & Citations: [1]Zhu GD, et al. Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Arylmodifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides. J Med Chem. 2001 Oct 11;44(21):3469-87.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported