ICAM-1-IN-1

ICAM-1-IN-1

• CAS Number: 251994-14-6
• UNSPSC Description: ICAM-1-IN-1 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC50 values of 7 and 5 nM, respectively.
• Target Antigen: Integrin
• Type: Reference compound
• Related Pathways: Cytoskeleton
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/Thieno[2,3-c]pyridine-2-carboxamide,_4-_4-bromophenoxy_-N-methyl-.html
• Purity: 99.93
• Solubility: DMSO : ≥ 135 mg/mL
• Smiles: O=C(C(S1)=CC2=C1C=NC=C2OC3=CC=C(Br)C=C3)NC
• Molecular Weight: 363.23
• References & Citations: [1]Zhu GD, et al. Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Arylmodifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides. J Med Chem. 2001 Oct 11;44(21):3469-87.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported