Z-Gly-Pro-Arg-AMC (hydrochloride)

Z-Gly-Pro-Arg-AMC (hydrochloride)

• CAS Number: 201928-42-9
• UNSPSC Description: Z-Gly-Pro-Arg-AMC hydrochloride a fluorescent trypsin and cathepsin K substrate. Z-Gly-Pro-Arg-AMC hydrochloride can be used to determine trypsin and cathepsin K activity[1][2].
• Target Antigen: Cathepsin
• Type: Peptides
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/z-gly-pro-arg-amc-hydrochloride.html
• Purity: 98.63
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C(CNC(OCC3=CC=CC=C3)=O)=O)=O)=O)C=C1O4)=CC4=O.Cl
• Molecular Weight: 656.13
• References & Citations: [1]Mosztbacher D, et al. Measuring digestive protease activation in the mouse pancreas. Pancreatology. 2020 Mar;20(2):288-292.|[2]Li WA, et al. Detection of femtomole quantities of mature cathepsin K with zymography. Anal Biochem. 2010 Jun 1;401(1):91-8.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported