2'-Fucosyllactose

CAT: 0804-HY-N9965-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N9965-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines[1][2].
CAS Number
[41263-94-9]
Product Name Alternative
2'-FL
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/2-fucosyllactose.html
Purity
99.97
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)O[C@H]2[C@H]([C@@H]([C@@H]([C@@H](O2)C)O)O)O
Molecular Formula
C18H32O15
Molecular Weight
488.44
Precautions
H302, H315, H319, H335
References & Citations
[1]He Y, et, al. The human milk oligosaccharide 2'-fucosyllactose modulates CD14 expression in human enterocytes, thereby attenuating LPS-induced inflammation. Gut. 2016 Jan;65 (1) :33-46.|[2]Eiwegger T, et, al. Human milk--derived oligosaccharides and plant-derived oligosaccharides stimulate cytokine production of cord blood T-cells in vitro. Pediatr Res. 2004 Oct;56 (4) :536-40.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
Phase 2

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