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VPC12249

CAT: 0804-HY-129808Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129808Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VPC12249 is a competitive dual LPA1/LPA3 antagonist with Ki values of 137nM and 428 nM, respectively. VPC12249 inhibits calcium mobilization in HEK293T cells with a Ki value of ~130 nM. VPC12249 is promising for research of ovarian cancer and hypertensive diseases[1].
CAS Number
403520-23-0
UNSPSC
12352005
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vpc12249.html
Smiles
CCCCCCCC/C=C\CCCCCCCC(N[C@@H](CC1=CC=C(OCC2=CC=CC=C2)C=C1)COP(O)(O)=O)=O
Molecular Formula
C34H52NO6P
Molecular Weight
601.75
References & Citations
[1]Heise CE, et al. Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: discovery of a LPA1/LPA3 receptor antagonist. Mol Pharmacol. 2001 Dec;60 (6) :1173-80.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
GTR19196193-01VPC12249

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