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Xanthoplanine

CAT: 0804-HY-N1064-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1064-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Xanthoplanine, isolated from theroot of Xylopia parviflora, fully inhibits the EC50 ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC50 values of 9 μM (alpha7) and 5 μM (alpha4beta2) [1].
CAS Number
6872-88-4
UNSPSC
12352005
Target
NAChR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/xanthoplanine.html
Solubility
10 mM in DMSO
Smiles
C[N+]1(C)CCC2=CC(OC)=C(OC)C3=C2[C@]1([H])CC4=CC(O)=C(OC)C=C34
Molecular Formula
C21H26NO4
Molecular Weight
356.43
References & Citations
[1]Iturriaga-Vásquez P, et al. Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers.Bioorg Med Chem. 2007 May 15;15 (10) :3368-72.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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