Xanthoplanine

• Description :

  Xanthoplanine, isolated from theroot of Xylopia parviflora, fully inhibits the EC50 ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC50 values of 9 μM (alpha7) and 5 μM (alpha4beta2) [1].

• UNSPSC :

  12352005

• Target :

  NAChR

• Type :

  Natural Products

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/xanthoplanine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[N+]1(C)CCC2=CC(OC)=C(OC)C3=C2[C@]1([H])CC4=CC(O)=C(OC)C=C34

• Molecular Formula :

  C21H26NO4

• Molecular Weight :

  356.43

• References & Citations :

  [1]Iturriaga-Vásquez P, et al. Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers.Bioorg Med Chem. 2007 May 15;15 (10) :3368-72.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [6872-88-4]