SMARCA-BD ligand 1 for PROTAC (dihydrochloride)

• UNSPSC Description:

  SMARCA-BD ligand 1 for PROTAC dihydrochloride is a compound that binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC[1].

• Target Antigen:

  Ligands for Target Protein for PROTAC

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/smarca-bd-ligand-1-for-protact-dihydrochloride.html

• Purity:

  98.56

• Solubility:

  DMSO : 2.7 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  OC1=CC=CC=C1C2=NN=C(N)C(N3CCNCC3)=C2.[H]Cl.[H]Cl

• Molecular Weight:

  344.24

• References & Citations:

  [1]Farnaby W, et al. BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat Chem Biol. 2019 Jul;15(7):672-680.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  2369053-68-7