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Phosphorylcholine

CAT: 0804-HY-B2233B-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2233B-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phosphatidylcholine is the main phospholipid component in eukaryotic biofilms. Phosphatidylcholine exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine exhibits a surprising range of immunomodulatory properties[1].
CAS Number
3616-04-4
Product Name Alternative
Phosphocholine
UNSPSC
12352211
Target
Adrenergic Receptor; Endogenous Metabolite
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/phosphorylcholine-1.html
Purity
98.0
Solubility
DMSO : < 1 mg/mL|Ethanol : 4 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=P(OCC[N+](C)(C)C)([O-])O
Molecular Formula
C5H14NO4P
Molecular Weight
183.14
References & Citations
[1]Harnett W, et al. Phosphorylcholine: friend or foe of the immune system? Immunol Today. 1999 Mar;20 (3) :125-9.|[2]Tu S, et al., Enhancement of cellular uptake and antitumor efficiencies of micelles with phosphorylcholine. Macromol Biosci. 2011 Oct 10;11 (10) :1416-25.|[3]Cansev M, et al., Choline, CDP-choline or phosphocholine increases plasma glucagon in rats: involvement of the peripheral autonomic nervous system. Eur J Pharmacol. 2008 Jul 28;589 (1-3) :315-22.|[4]Caligiuri G, et al., Phosphorylcholine-targeting immunization reduces atherosclerosis. J Am Coll Cardiol. 2007 Aug 7;50 (6) :540-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Citation 01
Adv Sci (Weinh) . 2024 Dec 4:e2411276.|Anal Chem. 2025 May 13;97 (18) :9827-9835.|JCI Insight. 2021 Oct 22;6 (20) :e151911.|Nat Commun. 2023 Mar 24;14 (1) :1631.|Nature. 2025 Jul;643 (8070) :192-200.|NPJ Biofilms Microbiomes. 2023 Sep 4;9 (1) :62.|Patent. US20250160318A1.|Virulence. 2025 Dec;16 (1) :2490208.|J Physiol Biochem. 2022 May;78 (2) :355-363.

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