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Androsin

CAT: 0804-HY-N1399-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1399-01Size:5 mg
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Description
Androsin is an active compound isolated from Picrorhiza Kurroa Royle ex Benth. Androsin activates AMPKα/PI3K/Beclin1/LC3 signaling pathway, inhibits SREBP1c/FASN signaling pathway. Androsin can be used in research of asthma and non-alcoholic fatty liver disease (NAFLD) . Androsin is orally active[1][2].
CAS Number
531-28-2
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
AMPK; Autophagy; PI3K
Type
Natural Products
Related Pathways
Autophagy; Epigenetics; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/androsin.html
Purity
99.94
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C(OC)=C1)=O
Molecular Formula
C15H20O8
Molecular Weight
328.31
Precautions
H302, H315, H319, H335
References & Citations
[1]Dorsch W, et al. Antiasthmatic effects of Picrorhiza kurroa: androsin prevents allergen- and PAF-induced bronchial obstruction in guinea pigs. Int Arch Allergy Appl Immunol. 1991;95 (2-3) :128-33.|[2]Singh A, et al., Androsin alleviates non-alcoholic fatty liver disease by activating autophagy and attenuating de novo lipogenesis. Phytomedicine. 2024 Jul;129:155702.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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