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Geranylgeraniol (Standard)

CAT: 0804-HY-W011474R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W011474R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model[1][2][3][4].
CAS Number
24034-73-9
UNSPSC
12352211
Target
NF-κB; Reference Standards
Type
Reference Standards
Related Pathways
NF-κB; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/geranylgeraniol-standard.html
Purity
98.93
Smiles
C/C(C)=C\CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CO
Molecular Formula
C20H34O
Molecular Weight
290.48
References & Citations
[1]Saputra WD, et al. Geranylgeraniol Inhibits Lipopolysaccharide-Induced Inflammation in Mouse-Derived MG6 Microglial Cells via NF-κB Signaling Modulation. Int J Mol Sci. 2021 Sep 29;22 (19) :10543. |[2]Marcuzzi A, et al. Geranylgeraniol and Neurological Impairment: Involvement of Apoptosis and Mitochondrial Morphology. Int J Mol Sci. 2016 Mar 11;17 (3) :365. |[3]Preece K, et al. A toxicological evaluation of geranylgeraniol. Regul Toxicol Pharmacol. 2021 Aug;124:104975. |[4]Giriwono PE, et al. Dietary supplementation with geranylgeraniol suppresses lipopolysaccharide-induced inflammation via inhibition of nuclear factor-κB activation in rats. Eur J Nutr. 2013 Apr;52 (3) :1191-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards