Recombinant Human NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3), Partial

• Gene Name:

  [NLRP3]

• NCBI Gene ID:

  114548

• Storage Conditions:

  The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
  Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

• Specificity:

  Predominantly expressed in macrophages. Also expressed in dendritic cells, B- and T-cells (at protein level) (PubMed:11786556) (PubMed:17164409). Expressed in LPS-treated granulocytes, but not in resting cells (at protein level) (PubMed:17164409). Expression in monocytes is very weak (at protein level) (PubMed:17164409). Expressed in stratified non-keratinizing squamous epithelium, including oral, esophageal and ectocervical mucosa and in the Hassall's corpuscles in the thymus. Also, detected in the stratified epithelium covering the bladder and ureter (transitional mucosa) (at protein level) (PubMed:17164409). Expressed in chondrocytes (PubMed:12032915). Expressed at low levels in resting osteoblasts (PubMed:17907925).

• Other Gene Names:

  [NLRP3; NLRP3; AII; AVP; FCU; MWS; FCAS; KEFH; CIAS1; FCAS1; NALP3; C1orf7; CLR1.1; DFNA34; PYPAF1; AGTAVPRL; C1orf7; CIAS1; NALP3; PYPAF1; CLR1.1]

• Short Name:

  [NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3)]

• Other Product Names:

  [NACHT, LRR and PYD domains-containing protein 3 isoform b; NACHT, LRR and PYD domains-containing protein 3; NACHT, LRR and PYD domains-containing protein 3; NLR family pyrin domain containing 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1]

• NCBI GI Number:

  34878690

• NCBI Accession Number:

  NP_899632

• NCBI GB Accession Number:

  NM_183395.2

• Uniprot Accession Number:

  Q96P20

• CAS Number:

  9000-83-3