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Xanthoangelol

CAT: 0804-HY-111588-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-111588-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity. Xanthoangelol inhibits monoamine oxidases. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells[1][2][3][4].
CAS Number
62949-76-2
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
AMPK; Apoptosis; Bacterial; Caspase; Monoamine Oxidase
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Epigenetics; Neuronal Signaling; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xanthoangelol.html
Purity
99.88
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(/C=C/C1=CC=C(O)C=C1)C2=CC=C(O)C(C/C=C(C)/CC/C=C(C)/C)=C2O
Molecular Formula
C25H28O4
Molecular Weight
392.49
Precautions
H302, H312, H332
References & Citations
[1]Li Y, et al. Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses. Obesity (Silver Spring) . 2016 Nov;24 (11) :2351-2360.|[2]Inamori Y, et al. Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI. Chem Pharm Bull (Tokyo) . 1991 Jun;39 (6) :1604-5.|[3]Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul) . 2013 May 30;21 (3) :234-40.|[4]Keiichi TABATA, et al. Xanthoangelol, a Major Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma and Leukemia Cells. Biol. Pharm. Bull. 28 (8) 1404-1407 (2005) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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