Pep2m, myristoylated
CAT:
804-HY-P1399
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Pep2m, myristoylated
- CAS Number: 1423381-07-0
- UNSPSC Description: Pep2m, myristoylated (Myr-Pep2m) is a cell-permeable peptide. Pep2m, myristoylated can disrupt the protein kinase ζ (PKMζ) downstream targets, N-ethylmaleimide-sensitive factor/glutamate receptor subunit 2 (NSF/GluR2) interactions. PKMζ is an autonomously active isozyme of protein kinase C (PKC)[1][2].
- Target Antigen: PKC
- Type: Peptides
- Related Pathways: Epigenetics;TGF-beta/Smad
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/pep2m-myristoylated.html
- Solubility: 10 mM in DMSO
- Smiles: CCCCCCCCCCCCCC([K])=O.[R][M]([V][*](N([Q])[*])[K])[K]
- Molecular Weight: 1383.81
- References & Citations: [1]Yudong Yao, et al. PKMζ Maintains Late Long-Term Potentiation by N-Ethylmaleimide-Sensitive Factor/GluR2-Dependent Trafficking of Postsynaptic AMPA Receptors. J Neurosci. 2008 Jul 30; 28(31): 7820-7827.|[2]Nicole C George, et al. Sex differences in the contributions of spinal atypical PKCs and downstream targets to the maintenance of nociceptive sensitization. Mol Pain. 2019; 15: 1744806919840582.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported