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8 Hydroxy PIPAT (oxalate)

CAT: 0804-HY-101225Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-101225Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that promotes the release of histamine from enteric mast cells. 8 Hydroxy PIPAT oxalate activates serotonergic signaling pathways, leading to the degranulation of mast cells in both guinea pig and human intestinal preparations. 8 Hydroxy PIPAT oxalate enhances the spontaneous release of histamine, which may contribute to the regulation of gastrointestinal functions. 8 Hydroxy PIPAT oxalate has potential implications for understanding and treating functional gastrointestinal disorders such as irritable bowel syndrome.
CAS Number
1451210-48-2
UNSPSC
12352005
Target
5-HT Receptor; Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/8-hydroxy-pipat-oxalate.html
Smiles
OC(C(O)=O)=O.OC1=C2C(CCC(C2)N(CCC)C/C=C/I)=CC=C1
Molecular Formula
C18H24INO5
Molecular Weight
461.29
References & Citations
[1]Mast cell expression of the serotonin1A receptor in guinea pig and human intestine
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor

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