8 Hydroxy PIPAT (oxalate)

8 Hydroxy PIPAT (oxalate)

• CAS Number: 1451210-48-2
• UNSPSC Description: 8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that promotes the release of histamine from enteric mast cells. 8 Hydroxy PIPAT oxalate activates serotonergic signaling pathways, leading to the degranulation of mast cells in both guinea pig and human intestinal preparations. 8 Hydroxy PIPAT oxalate enhances the spontaneous release of histamine, which may contribute to the regulation of gastrointestinal functions. 8 Hydroxy PIPAT oxalate has potential implications for understanding and treating functional gastrointestinal disorders such as irritable bowel syndrome.
• Target Antigen: Histamine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/8-hydroxy-pipat-oxalate.html
• Smiles: OC(C(O)=O)=O.OC1=C2C(CCC(C2)N(CCC)C/C=C/I)=CC=C1
• Molecular Weight: 461.29
• References & Citations: [1]Mast cell expression of the serotonin1A receptor in guinea pig and human intestine
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported