rac cis-Moxifloxacin-d4 (hydrochloride)

rac cis-Moxifloxacin-d4 (hydrochloride)

• CAS Number: 1217802-65-7
• UNSPSC Description: rac cis-Moxifloxacin-d4 (hydrochloride) is the deuterium labeled Moxifloxacin hydrochloride. Moxifloxacin Hydrochloride (BAY 12-8039) is an oral 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia[1][2].
• Target Antigen: Antibiotic; Bacterial; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Anti-infection;Others
• Field of Research: Infection
• Solubility: 10 mM in DMSO
• Smiles: O(C)C1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3C([C@]4([C@@](C3([2H])[2H])(NCCC4)[H])[H])([2H])[2H])C5CC5.Cl
• Molecular Weight: 441.92
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Culley CM, et al. Moxifloxacin: clinical efficacy and safety. Am J Health Syst Pharm. 2001 Mar 1;58(5):379-88.|[3]Balfour JA, et al. Moxifloxacin: a review of its clinical potential in the management of community-acquired respiratory tract infections. Drugs. 2000 Jan;59(1):115-39.|[4]Grayo S, et al. Comparison of the in vitro efficacies of moxifloxacin and amoxicillin against Listeria monocytogenes. Antimicrob Agents Chemother. 2008 May;52(5):1697-702.|[5]Ioannidis O, et al. Effect of moxifloxacin on survival, lipid peroxidation and inflammation in immunosuppressed rats with soft tissue infection caused by Stenotrophomonas maltophilia. Microbiol Immunol. 2014 Feb;58(2):96-102.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported