Fexofenadine (hydrochloride)
CAT:
804-HY-B0801A-02
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Fexofenadine (hydrochloride)
- CAS Number: 153439-40-8
- UNSPSC Description: Fexofenadine (MDL-16455) hydrochloride is an orally active and nonsedative H1 receptor antagonist. Fexofenadine hydrochloride can be used in allergic rhinitis and chronic idiopathic urticarial research[1][2][3].
- Target Antigen: Histamine Receptor
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology; Cancer
- Assay Protocol: https://www.medchemexpress.com/Fexofenadine-hydrochloride.html
- Purity: 99.86
- Solubility: DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(O)C(C)(C)C1=CC=C(C(O)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2)C=C1.[H]Cl
- Molecular Weight: 538.12
- References & Citations: [1]Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4(3):367-75.|[2]Park IH, et al. Histamine Promotes the Release of Interleukin-6 via the H1R/p38 and NF-κB Pathways in Nasal Fibroblasts. Allergy Asthma Immunol Res. 2014 Nov;6(6):567-72.|[3]Ming X, et al. Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters. Mol Pharm. 2011 Oct 3;8(5):1677-86.Int Immunopharmacol. 2023 Feb 8;116:109637.|Adv Mater Technol. 2023 Jan 29.|Biomed Pharmacother. 2024 Apr 30:175:116644.|Pharmacol Res. 2023 Mar 10;106724.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched