Platycodin D

Platycodin D

• CAS Number: 58479-68-8
• UNSPSC Description: Platycodin D is a saponin isolated from Platycodon grandiflorus, acts as an activator of AMPKα, with anti-obesity property. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D[1][2].
• Target Antigen: AMPK; Wnt
• Type: Natural Products
• Related Pathways: Epigenetics;PI3K/Akt/mTOR;Stem Cell/Wnt
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/platycodin-d.html
• Purity: 99.93
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: O=C([C@]1(CCC(C)(C)C2)[C@]2([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(C[C@H](O)[C@H](O[C@]([C@@H]([C@@H](O)[C@@H]6O)O)([H])O[C@@H]6CO)C5(CO)CO)C)[C@]3(C)C[C@H]1O)O[C@H](OC[C@H](O)[C@@H]7O)[C@@H]7O[C@@](O[C@@H](C)[C@H](O[C@@](OC[C@@H](O)[C@@H]8O[C@@](OC[C@]9(O)CO)([H])[C@@H]9O)([H])[C@@H]8O)[C@H]%10O)([H])[C@@H]%10O
• Molecular Weight: 1225.32
• References & Citations: [1]Kim HL, et al. Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis. Phytomedicine. 2019 Jan;52:254-263.|[2]Lee H, et al. WNT/β-catenin pathway mediates the anti-adipogenic effect of platycodin D, a natural compound found in Platycodon grandiflorum. Life Sci. 2011 Sep 12;89(11-12):388-94.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported