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Guaifenesin

CAT: 0804-HY-B0264-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0264-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough[1][2].
CAS Number
93-14-1
Product Name Alternative
Guaiacol glyceryl ether; Guaiphenesin; Glycerol guaiacolate
UNSPSC
12352005
Hazard Statement
H302
Target
Mucin
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Guaifenesin.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic; warming)
Smiles
OCC(O)COC1=CC=CC=C1OC
Molecular Formula
C10H14O4
Molecular Weight
198.22
Precautions
H302
References & Citations
[1]Bennett, S., N. Hoffman, and M. Monga, Ephedrine- and guaifenesin-induced nephrolithiasis. J Altern Complement Med, 2004. 10 (6) : p. 967-9.|[2]Dicpinigaitis PV, et, al. Effect of guaifenesin on cough reflex sensitivity. Chest. 2003 Dec;124 (6) :2178-81.|[3]Seagrave J, et al. Effect of guaifenesin on mucin production, rheology, and mucociliary transport in differentiated human airway epithelial cells. Exp Lung Res. 2011 Dec;37 (10) :606-14.|[4]Seagrave J, et al. Effects of guaifenesin, N-acetylcysteine, and ambroxol on MUC5AC and mucociliary transport in primary differentiated human tracheal-bronchial cells. Respir Res. 2012 Oct 31;13 (1) :98.|[5]Kagan L, et al. Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model. Pulm Pharmacol Ther. 2009 Jun;22 (3) :260-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched

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